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Resource · Board submission by state2026 edition

NP & PA collaborative
agreements, by state.

A 28-state operational reference to what NPs, PAs, and their collaborating physicians must actually file — and where board approval is required before a single patient is seen. Educational only; confirm current requirements with counsel.

Board submission + approval required · 11Board submission required · 16Prescriptive-authority filings · 1

Board submission + approval required

(11)

Alabama

AL

Board of Medical Examiners and Board of Nursing jointly approve collaborative practice applications for CRNPs, CNMs, and PAs.

Nurse Practitioner: Collaborating physician initiates via the Licensee Portal and submits the Standard Protocol, QA plan, and Commencement of Collaborative Practice form. QACSC required for controlled substances.

Physician Assistant: Application for Registration of PA, Core Duties/Scope of Practice, Disclosure of Existing Supervisory Agreement, and (if prescribing) Formulary for Non-Controlled Prescribing filed with the Alabama Board of Medical Examiners.

Alaska

AK

PAs must file a collaborative plan; the plan is only valid after a board representative approves it and it is noted on the license.

Physician Assistant: Collaborative plan submitted to the board; a copy must remain available for public review at the place of employment.

Arkansas

AR

APRNs with prescriptive authority must have a current Collaborative Practice Agreement on file with the Arkansas State Board of Nursing before practicing.

Nurse Practitioner: Submit CPA (PDF) via the Arkansas Nurse Portal message center; do not practice until an approval letter is issued.

Physician Assistant: Delegation agreement defining scope and supervision program filed with the board.

Indiana

IN

APRNs must file the Collaborative Practice Agreement with the Indiana State Board of Nursing before prescribing; changes and terminations must also be reported.

Nurse Practitioner: Original signatures required; updates must be submitted whenever the agreement changes or ends.

Kentucky

KY

Kentucky requires board-approved CAPA forms for NPs and a supervision application for PAs before practice begins.

Nurse Practitioner: CAPA-NS (non-controlled) and CAPA-CS (controlled substances) forms completed by the physician and NP; CAPA-CS requires Board of Nursing approval.

Physician Assistant: Application to Supervise a Physician Assistant filed by the collaborating physician.

Maine

ME

During the 24-month supervision period, the NP's supervising relationship must be approved by the Board within 15 days of starting employment.

Nurse Practitioner: Application for Approval of a Supervising Relationship, fee, and letter of intent submitted to the Maine Board of Nursing.

Missouri

MO

For controlled-substance prescribing, the collaborating physician files a Notice of Delegated Prescriptive Authority and the NP files a Controlled Substance Prescriptive Authority Application with the Missouri Board of Nursing.

Nurse Practitioner: Physician Notice of Delegated Prescriptive Authority + NP Controlled Substance application filed with the Board of Nursing.

New York

NY

Newly certified NPs must file Form 4NP — Verification of Collaborative Agreement and Practice Protocol — with the New York State Education Department within 90 days of starting practice.

Nurse Practitioner: Form 4NP filed with NYSED within 90 days of starting practice.

North Carolina

NC

NPs new to North Carolina must submit an Initial Approval to Practice and receive an approval number from the NC Medical Board and Board of Nursing before beginning employment.

Nurse Practitioner: Initial Approval to Practice application; approval number required on prescriptions.

Texas

TX

The supervising physician registers each APRN in the TMB's Online Supervision and Prescriptive Delegation Registration System — no paper forms are accepted.

Nurse Practitioner: Physician-completed online delegation registration in the TMB system covering scope, sites, and formulary.

Wyoming

WY

The supervising physician submits a Supervising Physician Application, and PA changes are reported using the state's change-of-supervision form.

Physician Assistant: Supervising Physician Application + change forms filed with the Wyoming Board of Medicine.

Board submission required

(16)

Florida

FL

Physicians must notify the Board within 30 days of entering — or terminating — a supervisory relationship, standing orders, or ARNP protocol.

Nurse Practitioner: APRN/EMT/Paramedic Protocol form mailed to the Board of Medicine per §458.348, F.S.

Physician Assistant: PA Supervision Data Form filed within 30 days of employment or any change in supervising physician.

Georgia

GA

Nurse Protocol Agreements between APRNs and collaborating physicians must be submitted to the Georgia Composite Medical Board within 30 days of signing, before the APRN begins practicing.

Nurse Practitioner: $150 registration; Nurse Protocol Agreement covers delegated acts, scope, and prescriptive authority.

Physician Assistant: Add/Change Supervising Physician application, Basic Job Description, and Forms B/H/J as applicable, filed with GCMB.

Hawaii

HI

A Verification – Supervising Physician form must be mailed to DCCA PVL Licensing Branch for each PA.

Physician Assistant: Verification – Supervising Physician form filed with DCCA.

Illinois

IL

The collaborating physician files Notice of Delegated Prescriptive Authority for Controlled Substances (APRN-CS or PHA-CS) with the Illinois Department of Financial and Professional Regulation.

Nurse Practitioner: APRN-CS notice filed by the collaborating physician when controlled-substance authority is delegated.

Physician Assistant: PHA-CS notice filed by the collaborating physician when controlled-substance authority is delegated.

Kansas

KS

PAs must submit a Physician Assistant Active Practice Request Form and Written Agreement to the board.

Physician Assistant: Active Practice Request Form + Written Agreement filed with the Kansas Board of Healing Arts.

Louisiana

LA

APRNs must notify the Louisiana State Board of Nursing within 30 days of any prescriptive-authority change, submitting the collaboration agreement with the notice.

Nurse Practitioner: Written notice + collaboration agreement filed with LSBN.

Physician Assistant: PA Notice of Intent to Practice filed with the board.

Maryland

MD

PAs must inform the Maryland Board of Physicians about the executed Collaboration Agreement before starting practice, filed through the Licensed Practitioner Portal.

Physician Assistant: Collaboration Agreement filed via mbp.state.md.us Licensed Practitioner Portal.

Massachusetts

MA

Nurse practitioners must apply for prescriptive authority with the Massachusetts Board of Registration in Nursing.

Nurse Practitioner: Prescriptive-authority application filed with the Board.

Mississippi

MS

Collaborating physicians must complete a Collaboration Information Form for each APRN and submit it through the MSBML online licensure gateway.

Nurse Practitioner: Collaboration Information Form filed via MSBML gateway.

Physician Assistant: PA registration required before practicing.

Nevada

NV

A physician intending to collaborate with an APRN must notify the Nevada State Board of Medical Examiners before collaboration begins.

Nurse Practitioner: Notification form signed by both parties filed with the Nevada Board of Medical Examiners.

Ohio

OH

NPs must update the Ohio Board of Nursing with the name and business address of each collaborating physician within 30 days.

Nurse Practitioner: Standard Care Arrangement update filed within 30 days.

Oklahoma

OK

APRNs seeking prescriptive authority must submit a notarized collaborative agreement to the board via the Nurse Portal for each supervising physician.

Nurse Practitioner: Notarized Agreement for Physician Supervision Advanced Practice Prescriptive Authority uploaded via Nurse Portal.

Pennsylvania

PA

CRNPs file the prescriptive-authority collaborative agreement with the Bureau of Professional and Occupational Affairs and keep the original at the primary practice location.

Nurse Practitioner: Copy of collaborative agreement filed with the Bureau; Board notified in writing of changes.

South Carolina

SC

APRNs must file an APRN Change of Practice Form for any new employment, practice change, or new collaborating physician, and mail an APRN Prescription Authority Application to the Board of Nursing.

Nurse Practitioner: Change of Practice Form + Prescription Authority Application mailed to the SC Board of Nursing.

Physician Assistant: PA registration and supervision documentation required with the Board of Medical Examiners.

Tennessee

TN

Before prescribing, APRNs submit the Notice and Formulary form to the Tennessee Board of Nursing, signed by both the APRN and supervising physician.

Nurse Practitioner: Notice and Formulary form filed with the TN Board of Nursing.

West Virginia

WV

Collaborative and supervision agreements are filed with the applicable West Virginia board before practice begins.

Nurse Practitioner: Collaborative agreement filed with the WV Board of Nursing (or Osteopathic/Medicine board as applicable).

Physician Assistant: Supervising physician application and PA registration filed with the board.

Prescriptive-authority filings

(1)

Colorado

CO

Additional prescriptive-authority forms are required in Colorado, including proposed mentorship documentation and the Provisional-to-Full RXN application after 750 mentorship hours.

Nurse Practitioner: New Application, Online Checklist, Proposed Mentorship Form, and reinstatement forms via the Colorado DPO Nursing portal.

FAQ

What clinic owners ask before opening a new state.

Which states require a collaborative or supervision agreement to be submitted to a state board?

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At least 28 states require some form of board submission for nurse practitioner or physician assistant practice, including Alabama, Alaska, Arkansas, Colorado, Florida, Georgia, Hawaii, Illinois, Indiana, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Mississippi, Missouri, Nevada, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Tennessee, Texas, West Virginia, and Wyoming.

What's the difference between 'board submission required' and 'board submission + approval required'?

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Submission-only states accept the filing and let practice begin once the paperwork is on file — Florida, Georgia, Hawaii, Illinois, Louisiana, Maryland, Massachusetts, Mississippi, Nevada, Ohio, Oklahoma, Pennsylvania, South Carolina, and Tennessee are examples. Approval states require the board to formally approve the collaborative or supervisory agreement before the NP or PA may see patients — including Alabama, Arkansas, Indiana, Kentucky, Maine, Missouri, New York, North Carolina, Texas, and Wyoming.

Who submits the collaborative or supervision agreement — the physician or the NP/PA?

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It varies by state. In Alabama, Florida, Illinois, Nevada, and Texas, the collaborating or supervising physician initiates the filing. In Arkansas, Louisiana, New York, Oklahoma, Pennsylvania, South Carolina, and Tennessee, the NP or PA typically submits. Several states — including Kentucky, Georgia, and Indiana — require joint completion and signatures from both parties.

Are controlled-substance prescriptions filed differently?

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Yes. States like Alabama (QACSC), Colorado (Provisional-to-Full RXN), Illinois (APRN-CS / PHA-CS), Kentucky (CAPA-CS), and Missouri require separate controlled-substance authority filings on top of the base collaborative agreement.

How often do these filings need to be updated?

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Any change to the collaborating physician, practice location, scope, or termination of the agreement usually triggers a filing — most states specify 30 days (Florida, Louisiana, Ohio, Pennsylvania). Camino's quarterly compliance program catches these before they lapse.

Related: Corporate Practice of Medicine by state · Quarterly compliance attestations

Opening a new state? Let's map the filings first.

We'll pull the exact forms, signatures, and approval timelines for every state on your expansion plan — and wire them into your quarterly compliance rhythm.